Emory University Class of 2020
I am currently working on two projects: One, which I am doing in collaboration with Bruce Levin, is to determine the conditions under which a wide host range therapeutic phage from the Eliava Institute in Tbilisi, Georgia, PYO, can be maintained in and control the densities of Staphylococcus aureus populations. The second project, which we are doing in collaboration with Luciano Marraffini, is to elucidate the conditions under which selection mediated by lytic phage will favor the evolution and maintenance of CRISPR-Cas immunity in a Staphylococcus aureus construct capable of generating mutants resistant to these viruses. Of particular interest in project is evaluate the proposition that CRISPR-Cas evolved and is maintained as mechanism to protect bacteria from infections with virulent viruses.
For information about these projects, write to me at firstname.lastname@example.org